Renal complications and scleroderma renal crisis

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Renal complications and scleroderma renal crisis.

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Scleroderma renal crisis (SRC) is an infrequent but serious complication of systemic sclerosis (SSc). It is associated with increased vascular permeability, activation of coagulation cascade, and renin secretion, which may lead to the acute renal failure typically associated with accelerated hypertension. The histologic picture of SRC is that of a thrombotic microangiopathy process with promine...

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ژورنال

عنوان ژورنال: Rheumatology

سال: 2006

ISSN: 1462-0324,1462-0332

DOI: 10.1093/rheumatology/ken483